From the abstract:
Django co-creator Adrian Holovaty shares his ideas on the future of server-side Web frameworks. Are the current batch of frameworks getting long in the tooth? Should we really still be generating HTML from scratch on each page request? Can we automate some of the new best practices, such as Pjax?
No Django knowledge is necessary to understand this talk; the thoughts apply equally to Ruby on Rails and other circa-2005 frameworks.